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Aspirin Tames Pain-Causing InflammationA well-known non-steroidal anti-inflammatory that has been used for more than a century, aspirin works is by blocking the body’s production of prostaglandins in the peripheral nervous system. Aspirin helps to prevent the transmission of pain signals to the brain by stopping the production of prostaglandins. |
Acetaminophen: The Tried-and-True Pain RelieverAcetaminophen, like aspirin, also appears to inhibits enzymes in the body that produce pain-causing prostaglandins. However, while aspirin inhibits prostaglandins in the peripheral nervous system, acetaminophen appears to focus its pain-fighting power in the central nervous system. This allows you to tolerate more pain, therefore providing pain relief. |
Caffeine: The AmplifierCaffeine has been shown to increase the potency of aspirin and acetaminophen—the two pain relievers in Excedrin Migraine — by up to 40 percent. This means less acetaminophen and aspirin is needed to relieve your migraine pain when combined with caffeine. |
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